Shifting emphasis from pharmacogenomics to theragnostics

被引:99
作者
Ozdemir, Vural [1 ]
Williams-Jones, Bryn
Glatt, Stephen J.
Tsuang, Ming T.
Lohr, James B.
Reist, Christopher
机构
[1] So Calif Inst Res & Educ, Biomarker & Clin Pharmacol Unit, VA Long Beach Healthcare Syst, Irvine, CA USA
[2] Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA USA
[3] Mental Illness Res Educ & Clin Ctr, Long Beach, CA USA
[4] Mental Illness Res Educ & Clin Ctr, San Diego, CA USA
[5] Mental Illness Res Educ & Clin Ctr, Los Angeles, CA USA
[6] Univ Montreal, Grp Rech Bioeth, Montreal, PQ, Canada
[7] Univ Montreal, Dept Med Sociale & Prevent, Montreal, PQ, Canada
[8] Univ Calif San Diego, Ctr Behav Genom, San Diego, CA 92103 USA
[9] Univ Calif San Diego, Psychopharmacol Res Initiat Ctr Excellence, San Diego, CA 92103 USA
关键词
D O I
10.1038/nbt0806-942
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
What will be the role of theragnostic patents in upstream and downstream biomarker research?
引用
收藏
页码:942 / 947
页数:6
相关论文
共 38 条
[1]   Pharmacogenomic-guided rational therapeutic drug monitoring: Conceptual framework and application platforms for atypical antipsychotics [J].
Albers, LJ ;
Ozdemir, V .
CURRENT MEDICINAL CHEMISTRY, 2004, 11 (03) :297-312
[2]   Excess in the pharmaceutical industry [J].
Angell, M .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2004, 171 (12) :1451-1453
[3]  
Baird P, 1998, PERSPECT BIOL MED, V41, P391
[4]  
Brown N., 2003, SCI STUD, V16, P3, DOI DOI 10.23987/STS.55152
[5]   Policy conflicts: Gene patents and health care in Canada [J].
Caulfield, T .
COMMUNITY GENETICS, 2005, 8 (04) :223-227
[6]   Geneticists question fees for use of patented 'junk' DNA [J].
Dennis, C .
NATURE, 2003, 423 (6936) :105-105
[7]   The price of innovation: new estimates of drug development costs [J].
DiMasi, JA ;
Hansen, RW ;
Grabowski, HG .
JOURNAL OF HEALTH ECONOMICS, 2003, 22 (02) :151-185
[8]   Will pharmacogenomics alter the role of patents in drug development? [J].
Eisenberg, RS .
PHARMACOGENOMICS, 2002, 3 (05) :571-574
[9]   The complexities of predictive genetic testing [J].
Evans, JP ;
Skrzynia, C ;
Burke, W .
BMJ-BRITISH MEDICAL JOURNAL, 2001, 322 (7293) :1052-1056
[10]   Drug therapy - Pharmacogenomics - Drug disposition, drug targets, and side effects [J].
Evans, WE ;
McLeod, HL .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (06) :538-549