Drug therapy - Pharmacogenomics - Drug disposition, drug targets, and side effects

被引:1175
作者
Evans, WE
McLeod, HL
机构
[1] St Jude Childrens Res Hosp, Memphis, TN 38101 USA
[2] Univ Tennessee, Coll Pharm, Memphis, TN USA
[3] Univ Tennessee, Coll Med, Memphis, TN USA
[4] Washington Univ, Sch Med, St Louis, MO USA
关键词
D O I
10.1056/NEJMra020526
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:538 / 549
页数:12
相关论文
共 96 条
[1]   MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia [J].
Abbott, GW ;
Sesti, F ;
Splawski, I ;
Buck, ME ;
Lehmann, WH ;
Timothy, KW ;
Keating, MT ;
Goldstein, SAN .
CELL, 1999, 97 (02) :175-187
[2]   MDR1 pharmacogenetics:: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity [J].
Ameyaw, MM ;
Regateiro, F ;
Li, T ;
Liu, XH ;
Tariq, M ;
Mobarek, A ;
Thornton, N ;
Folayan, GO ;
Githang'a, J ;
Indalo, A ;
Ofori-Adjei, D ;
Price-Evans, DA ;
McLeod, HL .
PHARMACOGENETICS, 2001, 11 (03) :217-221
[3]   Pharmacogenetic prediction of clozapine response [J].
Arranz, MJ ;
Munro, J ;
Birkett, J ;
Bolonna, A ;
Mancama, D ;
Sodhi, M ;
Lesch, KP ;
Meyer, JFW ;
Sham, P ;
Collier, DA ;
Murray, RM ;
Kerwin, RW .
LANCET, 2000, 355 (9215) :1615-1616
[4]   Apolipoprotein E genotypes and response of plasma lipids and progression-regression of coronary atherosclerosis to lipid-lowering drug therapy [J].
Ballantyne, CM ;
Herd, JA ;
Stein, EA ;
Ferlic, LL ;
Dunn, JK ;
Gotto, AM ;
Marian, AJ .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (05) :1572-1578
[5]   Association of the MscI polymorphism of the dopamine D3 receptor gene with tardive dyskinesia in schizophrenia [J].
Basile, VS ;
Masellis, M ;
Badri, F ;
Paterson, AD ;
Meltzer, HY ;
Lieberman, JA ;
Potkin, SG ;
Macciardi, F ;
Kennedy, JL .
NEUROPSYCHOPHARMACOLOGY, 1999, 21 (01) :17-27
[6]   Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine [J].
Black, AJ ;
McLeod, HL ;
Capell, HA ;
Powrie, RH ;
Matowe, LK ;
Pritchard, SC ;
Collie-Duguid, ESR ;
Reid, DM .
ANNALS OF INTERNAL MEDICINE, 1998, 129 (09) :716-718
[7]   A family of drug transporters: The multidrug resistance-associated proteins [J].
Borst, P ;
Evers, R ;
Kool, M ;
Wijnholds, J .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (16) :1295-1302
[8]   Pharmacogenetics of the human drug-transporter gene MDR1:: impact of polymorphisms on pharmacotherapy [J].
Brinkmann, U ;
Roots, I ;
Eichelbaum, M .
DRUG DISCOVERY TODAY, 2001, 6 (16) :835-839
[9]  
Cargill M, 2000, Pharmacogenomics, V1, P27, DOI 10.1517/14622416.1.1.27
[10]   ENZYMATIC DEFICIENCY IN PRIMAQUINE-SENSITIVE ERYTHROCYTES [J].
CARSON, PE ;
FLANAGAN, CL ;
ICKES, CE ;
ALVING, AS .
SCIENCE, 1956, 124 (3220) :484-485