API-CALC 1.0: a computer program for calculating the average probability of identity allowing for substructure, inbreeding and the presence of close relatives

被引：44

作者：

Ayres, KL ^{[1
]}

Overall, ADJ

机构：

[1] Univ Reading, Sch Appl Stat, Reading, Berks, England

[2] Univ Edinburgh, ICAPB, Edinburgh EH8 9YL, Midlothian, Scotland

来源：

MOLECULAR ECOLOGY NOTES | 2004年 / 4卷 / 02期

关键词：

conservation genetics; DNA profiles; noninvasive sampling; probability of identity;

D O I：

10.1111/j.1471-8286.2004.00616.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Individual identification via DNA profiling is important in molecular ecology, particularly in the case of noninvasive sampling. A key quantity in determining the number of loci required is the probability of identity (PIave), the probability of observing two copies of any profile in the population. Previously this has been calculated assuming no inbreeding or population structure. Here we introduce formulae that account for these factors, whilst also accounting for relatedness structure in the population. These formulae are implemented in API-CALC 1.0, which calculates PIave for either a specified value, or a range of values, for F-IS and F-ST.

引用

页码：315 / 318

页数：4

共 10 条

[1] Allowing for within-subpopulation inbreeding in forensic match probabilities [J].