From Hype to Hope: The Gut Microbiota in Enteric Infectious Disease

被引：173

作者：

McKenney, Peter T. ^{[1
]}

Pamer, Eric G. ^{[1
,2
,3
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Sloan Kettering Inst, Immunol Program, New York, NY 10065 USA

[2] Mem Sloan Kettering Canc Ctr, Lucille Castori Ctr Microbes Inflammat & Canc, New York, NY 10065 USA

[3] Mem Sloan Kettering Canc Ctr, Dept Med, Infect Dis Serv, New York, NY 10065 USA

来源：

CELL | 2015年 / 163卷 / 06期

关键词：

CLOSTRIDIUM-DIFFICILE INFECTION; DAMAGE-RESPONSE FRAMEWORK; STEM-CELL TRANSPLANTATION; INTESTINAL MICROBIOTA; COMMENSAL BACTERIA; DIURNAL OSCILLATIONS; ANTIBIOTIC-TREATMENT; CIRCADIAN CLOCK; IMMUNE-SYSTEM; BILE-ACIDS;

D O I：

10.1016/j.cell.2015.11.032

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

One of the clearest functions of the gut microbiota in humans is resistance to colonization by enteric bacterial pathogens. Reconstitution of the microbiota offers an exciting therapeutic approach, but great challenges must be overcome.

引用

页码：1326 / 1332

页数：7

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