Calix[6]arene derivatives bearing sulfonate and alkyl groups as surfactants in Sc(OTf)3-catalyzed Mukaiyama aldol reactions in water

被引：43

作者：

Tian, HY

Chen, YJ

Wang, D ^{[1
]}

Zeng, CC

Li, CJ

机构：

[1] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China

[2] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 15期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0040-4039(00)00257-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Amphiphilic calix[6]arene derivatives 1a-b were found to be efficient surfactants for Sc(OTf)(3)-catalyzed Mukaiyama aldol reaction of silyl enol ethers with aldehydes in water. The results indicated that a hydrophobic microenvironment was formed in the reaction system, which is favorable to stabilize some labile silyl enol ethers and thus promotes the reactions. (C) 2000 Elsevier Science Ltd. All rights reserved.

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页码：2529 / 2532

页数：4

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