Lewis acid catalysis in micellar systems. Sc(OTf)(3)-catalyzed aqueous aldol reactions of silyl enol ethers with aldehydes in the presence of a surfactant

被引：145

作者：

Kobayashi, S ^{[1
]}

Wakabayashi, T ^{[1
]}

Nagayama, S ^{[1
]}

Oyamada, H ^{[1
]}

机构：

[1] JAPAN SCI & TECHNOL CORP,CREST,SHINJUKU KU,TOKYO 162,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(97)00854-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Scandium triflate (Sc(OTf)(3))-catalyzed aldol reactions of silyl enol ethers with aldehydes were successfully carried out in micellar systems. While the reactions proceeded sluggishly in water, remarkable enhancement of the reactivity was observed in the presence of a small amount of a surfactant. In these systems, versatile carbon-carbon bond-forming reactions proceeded in water without using any organic solvents. (C) 1997 Elsevier Science Ltd.

引用

页码：4559 / 4562

页数：4

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