Molecular recognition of bacterial phosphorelay proteins

被引：43

作者：

Varughese, KL ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Mol & Expt Med, Div Cellular Biol, La Jolla, CA 92037 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2002年 / 5卷 / 02期

关键词：

D O I：

10.1016/S1369-5274(02)00305-3

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The transfer of the phosphoryl group from a histidine kinase to a response regulator forms the basis of bacterial signal transduction. The critical question of how a component of a signal transduction system specifically associates with its partner to produce the ideal environment for phosphotransfer is addressed in this review in the light of the structure of the SpoOF-SpoOB complex in Bacillus subtilis.

引用

页码：142 / 148

页数：7

共 30 条

[21] NMR structure of the histidine kinase domain of the E-coli osmosensor EnvZ [J].

Tanaka, T ;

Saha, SK ;

Tomomori, C ;

Ishima, R ;

Liu, DJ ;

Tong, KI ;

Park, H ;

Dutta, R ;

Qin, L ;

Swindells, MB ;

Yamazaki, T ;

Ono, AM ;

Kainosho, M ;

Inouye, M ;

Ikura, M .

NATURE, 1998, 396 (6706) :88-92

[22]

Thomason P, 2000, J CELL SCI, V113, P3141

[23]

Tomomori C, 1999, NAT STRUCT BIOL, V6, P729

[24] Molecular recognition in signal transduction: The interaction surfaces of the Spo0F response regulator with its cognate phosphorelay proteins revealed by alanine scanning mutagenesis [J].

Tzeng, YL ;

Hoch, JA .

JOURNAL OF MOLECULAR BIOLOGY, 1997, 272 (02) :200-212

[25] Formation of a novel four-helix bundle and molecular recognition sites by dimerization of a response regulator phosphotransferase [J].

Varughese, KI ;

Madhusudan ;

Zhou, XZ ;

Whiteley, JM ;

Hoch, JA .

MOLECULAR CELL, 1998, 2 (04) :485-493

[26] 3-DIMENSIONAL SOLUTION STRUCTURE OF THE N-TERMINAL RECEIVER DOMAIN OF NTRC [J].

VOLKMAN, BF ;

NOHAILE, MJ ;

AMY, NK ;

KUSTU, S ;

WEMMER, DE .

BIOCHEMISTRY, 1995, 34 (04) :1413-1424

[27]

VOLZ K, 1991, J BIOL CHEM, V266, P15511

[28] Conservation of structure and function among histidine-containing phosphotransfer (HPt) domains as revealed by the crystal structure of YPD1 [J].

Xu, QP ;

West, AH .

JOURNAL OF MOLECULAR BIOLOGY, 1999, 292 (05) :1039-1050

[29] A transient interaction between two phosphorelay proteins trapped in a crystal lattice reveals the mechanism of molecular recognition and phosphotransfer in signal transduction [J].

Zapf, J ;

Sen, U ;

Madhusudan ;

Hoch, JA ;

Varughese, KI .

STRUCTURE, 2000, 8 (08) :851-862

[30] Phosphotransfer site of the chemotaxis-specific protein kinase CheA as revealed by NMR [J].

Zhou, HJ ;

Dahlquist, FW .

BIOCHEMISTRY, 1997, 36 (04) :699-710

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