A new entry to Amaryllidaceae alkaloids from carbohydrates:: total synthesis of (+)-vittatine

被引：32

作者：

Bohno, M ^{[1
]}

Imase, H ^{[1
]}

Chida, N ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 09期

关键词：

D O I：

10.1039/b402762k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The stereoselective and chiral synthesis of the Amaryllidaceae alkaloid, (+)-vittatine 1, is described; the quaternary carbon in I was generated by Claisen rearrangement of a cyclohexenol derived from D-glucose by way of a Ferrier's carbocyclisation reaction and a hexahydroindole skeleton was effectively constructed by intramolecular aminomercuration-demercuration, followed by Chugaev reaction.

引用

页码：1086 / 1087

页数：2

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