A chiral rhodium complex for rapid asymmetric transfer hydrogenation of imines with high enantioselectivity

被引：218

作者：

Mao, JM ^{[1
]}

Baker, DC ^{[1
]}

机构：

[1] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 06期

关键词：

D O I：

10.1021/ol990098q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A chiral rhodium complex, (R)-Cp*RhCl[(1S,2S)-p-TsNCH(C6H5)CH(C6H5)NH2] (1a, (S,S)-Cp*RhCITsDPEN), generated from [Cp*RhCl2](2) and (1S,2S) N-p-toluenesulfonyl-1,2-diphenylethylenediamine [(S,S) TsDPEN], and its enantiomer 1b were found to provide superior catalysts for the rapid, high yielding, asymmetric transfer hydrogenation of some heterocyclic imines, using an HCO2H-Et3N azeotrope as the hydrogen source.

引用

页码：841 / 843

页数：3

共 37 条

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