Presenile dementia syndromes: an update on taxonomy and diagnosis

被引：53

作者：

Greicius, MD

Geschwind, MD

Miller, BL

机构：

[1] Univ Calif San Francisco, Memory & Aging Ctr, Sch Med, Dept Neurol, San Francisco, CA 94117 USA

[2] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2002年 / 72卷 / 06期

关键词：

D O I：

10.1136/jnnp.72.6.691

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The four major degenerative dementias that often begin in presenescence: are reviewed. These are Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, and Creutzfeldt-Jakob disease. Their epidemiological, genetic, and clinical features are reviewed, and controversies in taxonomy arising from recent discoveries described. Particular attention is given to the pathological role of protein aggregation, which appears to be a factor in each disease.

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页码：691 / 700

页数：10

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