共 22 条
A differential geometry approach for biomedical image processing
被引:9
作者:
Demongeot, J
[1
]
Françoise, JF
Richard, M
Senegas, F
Baum, TP
机构:
[1] Univ Grenoble 1, Fac Med, UMR CNRS 5525, Lab TIMC IMAG, F-38700 La Tronche, France
[2] Univ Paris 06, Lab Geometrie Differentielle Syst Differentiels I, F-75252 Paris 05, France
关键词:
bio-arrays;
segmentation;
Gauss curvature;
peak detection;
D O I:
10.1016/S1631-0691(02)01459-2
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
We show in this paper how simple considerations about bio-arrays images lead to a peak segmentation allowing the genes activity analysis. Bio-arrays images have a particular structure and the aim of the paper is to present a mathematical method allowing their automatic processing. The differential geometry approach used here can be also employed for other types of images presenting grey level peaks corresponding to a functional activity or to a chemical concentration. The mathematical method is based on elementary techniques of differential geometry and dynamical systems theory and provides a simple efficient algorithm when the peaks to segment are isolated. (C) 2002 Academie des sciences/Editions scientifiques et medicales Elsevier SAS.
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页码:367 / 374
页数:8
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