Two-step preconcentration for analysis of exhaled gas of human breath with electronic nose

被引:41
作者
Cho, Seong M.
Kim, Young Jun
Heo, Gwi Suk
Shin, Sang-Man
机构
[1] Elect & Telecommun Res Inst, Biosensor Team, Basic Res Lab, Taejon 305350, South Korea
[2] Korea Res Inst Stand & Sci, Gas Metrol Grp, Taejon 305600, South Korea
关键词
preconcentration; electronic nose; adsorbent; breath analysis;
D O I
10.1016/j.snb.2005.10.050
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The two-step preconcentrator, which performs concentrating volatile organic compounds (VOCs) and removing water vapor from samples, was suggested for the analysis of the exhaled gas of human breath. The suggested two-step preconcentrator consisted of two separate adsorbent stages, and it was operated simply by the serial adsorption/desorption of these two adsorbent stages. By using an additional adsorbent stage, the performance of water removal was improved four times without loss of the VOCs, compared with that of the conventional single-step preconcentrator. The suggested two-step preconcentrator is considered to be widely applicable to many fields in which interference by water vapor is critical. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:50 / 57
页数:8
相关论文
共 27 条
[1]   Development of a preconcentration unit for a SAW sensor micro array and its use for indoor air quality monitoring [J].
Bender, F ;
Barié, N ;
Romoudis, G ;
Voigt, A ;
Rapp, A .
SENSORS AND ACTUATORS B-CHEMICAL, 2003, 93 (1-3) :135-141
[2]   Lung cancer identification by the analysis of breath by means of an array of non-selective gas sensors [J].
Di Natale, C ;
Macagnano, A ;
Martinelli, E ;
Paolesse, R ;
D'Arcangelo, G ;
Roscioni, C ;
Finazzi-Agrò, A ;
D'Amico, A .
BIOSENSORS & BIOELECTRONICS, 2003, 18 (10) :1209-1218
[3]   Use of compatible polymer blends to fabricate arrays of carbon black-polymer composite vapor detectors [J].
Doleman, BJ ;
Sanner, RD ;
Severin, EJ ;
Grubbs, RH ;
Lewis, NS .
ANALYTICAL CHEMISTRY, 1998, 70 (13) :2560-2564
[4]   Detection of volatile compounds correlated to human diseases through breath analysis with chemical sensors [J].
Fleischer, M ;
Simon, E ;
Rumpel, E ;
Ulmer, H ;
Harbeck, M ;
Wandel, M ;
Fietzek, C ;
Weimar, U ;
Meixner, H .
SENSORS AND ACTUATORS B-CHEMICAL, 2002, 83 (1-3) :245-249
[5]  
Gardner J. W., 1999, ELECT NOSES PRINCIPL
[6]   An electronic nose system to diagnose illness [J].
Gardner, JW ;
Shin, HW ;
Hines, EL .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 70 (1-3) :19-24
[7]   Dry purge for the removal of water from the solid sorbents used to sample volatile organic compounds from the atmospheric air [J].
Gawlowski, J ;
Gierczak, T ;
Pietruszyñska, Z ;
Gawrys, M ;
Niedzielski, J .
ANALYST, 2000, 125 (11) :2112-2117
[8]   Analyzing organic vapors in exhaled breath using a surface acoustic wave sensor array with preconcentration: Selection and characterization of the preconcentrator adsorbent [J].
Groves, WA ;
Zellers, ET ;
Frye, GC .
ANALYTICA CHIMICA ACTA, 1998, 371 (2-3) :131-143
[9]   Environmental temperature-independent gas sensor array based on polymer composite [J].
Ha, SC ;
Yang, Y ;
Kim, YS ;
Kim, SH ;
Kim, YJ ;
Cho, SM .
SENSORS AND ACTUATORS B-CHEMICAL, 2005, 108 (1-2) :258-264
[10]   Integrated and microheater embedded gas sensor array based on the polymer composites dispensed in micromachined wells [J].
Ha, SC ;
Kim, YS ;
Yang, Y ;
Kim, YJ ;
Cho, SM ;
Yang, H ;
Kim, YT .
SENSORS AND ACTUATORS B-CHEMICAL, 2005, 105 (02) :549-555