Molecular characterization of the integrons in Shigella strains isolated from patients with traveler's diarrhea

被引：31

作者：

Navia, MM ^{[1
]}

Ruiz, J ^{[1
]}

Vila, J ^{[1
]}

机构：

[1] Univ Barcelona, IDIBAPS, Hosp Clin, Inst Clin Infecc & Immunol,Serv Microbiol, E-08036 Barcelona, Spain

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2004年 / 48卷 / 03期

关键词：

genetic elements; antibiotic resistance; gene cassettes;

D O I：

10.1016/j.diagmicrobio.2003.10.007

中图分类号：

R51 [传染病];

学科分类号：

100401 [流行病与卫生统计学];

摘要：

The prevalence and characterization of Class 1 integrons has been performed in eighty three strains of Shigella spp., isolated between 1995 and 2000 from patients with traveler's diarrhea. A low prevalence (13.25%) was recorded. Nine different integrons were found among 11 multiresistant strains, with a total of 10 different gene cassettes encoding for resistance to trimethoprim (dfrA1, dfrA5, dfrA7, dfrA12, and dfrA15), aminoglycosides (aadA1a and aadA2), beta-lactam antibiotics (oxa2) or ORF with unknown function (orfD and orfF). A high prevalence of dfr and aad gene cassettes was observed. The low incidence of Class 1 integrons observed in this study is in contrast with the known facility that the Shigella genus has to gain and transfer plasmids. (C) 2004 Elsevier Inc. All rights reserved.

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收藏

页码：175 / 179

页数：5

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