Nanotopographic Carbon Nanotube Thin-Film Substrate Freezes Lateral Motion of Secretory Vesicles

被引：19

作者：

Zhang, Jing ^{[2
]}

Fu, Dongliang ^{[1
]}

Chan-Park, Mary B. ^{[2
]}

Li, Lain-Jong ^{[1
]}

Chen, Peng ^{[2
]}

机构：

[1] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore

[2] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637457, Singapore

来源：

ADVANCED MATERIALS | 2009年 / 21卷 / 07期

关键词：

REFLECTION FLUORESCENCE MICROSCOPY; CHROMAFFIN CELLS; PLASMA-MEMBRANE; EXOCYTOSIS; STIMULATION; BEHAVIOR; NEURONS;

D O I：

10.1002/adma.200801586

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thin-film carbon-nanotube networks can interface with living neuroenclocrine PC12 cells and support their growth and proliferation. Interestingly, as revealed by total-internal-reflection fluorescence microscopy, the nanoroughness created by the carbon-nanotube net physically deforms the 5 nm thick cell membrane with high local curvature and significantly impedes the lateral motion of subplasmalemmal secretory vesicles.

引用

页码：790 / +

页数：5

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