Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease

被引：45

作者：

Bao, Xianying ^{[1
,2
,3
,4
]}

Feng, Zemeng ^{[2
,3
,4
,5
]}

Yao, Jiming ^{[6
]}

Li, Tiejun ^{[1
,2
,3
,4
,5
]}

Yin, Yulong ^{[1
,2
,3
,4
]}

机构：

[1] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410128, Hunan, Peoples R China

[2] Chinese Acad Sci, Key Lab Agroecol Proc Subtrop Reg, Inst Subtrop Agr, Changsha 410125, Hunan, Peoples R China

[3] Natl Engn Lab Pollut Control & Waste Utilizat Liv, Changsha 410125, Hunan, Peoples R China

[4] Minist Agr, Hunan Prov Engn Res Ctr Hlth Livestock & Poultry, Sci Observing & Expt Stn Anim Nutr & Feed Sci Sou, Changsha 410125, Hunan, Peoples R China

[5] CICAPS, Hunan Coinnovat Ctr Anim Prod Safety, Changsha 410128, Hunan, Peoples R China

[6] Guangdong Wangda Grp Co Ltd, Guangdong Wangda Grp Academician Workstn Clean Fe, Guangzhou 510663, Guangdong, Peoples R China

来源：

MEDIATORS OF INFLAMMATION | 2017年 / 2017卷

关键词：

CONJUGATED 5-AMINOSALICYLIC ACID; EXPERIMENTAL COLITIS; L-ARGININE; ULCERATIVE-COLITIS; OXIDATIVE STRESS; HYDROGEN-SULFIDE; ATTENUATES INFLAMMATION; COLONIC-MUCOSA; IN-VITRO; TAURINE;

D O I：

10.1155/2017/6869259

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Inflammatory Bowel Disease (IBD) is a kind of chronic inflammation, which has increasing incidence and prevalence in recent years. IBDmainly divides intoCrohn's disease (CD) and ulcerative colitis (UC). It is hard to cure IBDcompletely, and novel therapies are urgently needed. Amino acids (AAs) and their metabolites are regarded as important nutrients for humans and animals and also play an important role in IBD amelioration. In the present study, the potential protective effects of AAs and their metabolites on IBD had been summarized with the objective to provide insights into IBD moderating using dietary AAs and their metabolites as a potential adjuvant therapy.

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页数：9

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