Landmark-based registration and measurement of magnetic resonance images: A reliability study

被引:19
作者
Arndt, S
Rajarethinam, R
Cizadlo, T
OLeary, D
Downhill, J
Andreasen, NC
机构
[1] UNIV IOWA, DEPT PREVENT MED & ENVIRONM HLTH, IOWA CITY, IA 52242 USA
[2] UNIV MICHIGAN, DEPT PSYCHIAT, ANN ARBOR, MI 48109 USA
[3] CUNY MT SINAI SCH MED, DEPT PSYCHIAT, NEW YORK, NY 10029 USA
关键词
morphometry; brain size; anterior commissure; posterior commissure;
D O I
10.1016/0925-4927(96)02904-6
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report a magnetic resonance imaging (MRI) study in a large number of subjects that examines various analytic techniques for anatomical landmark information. The initial issue involved interrater reliability in locating landmarks along the midsagittal plane, Another issue dealt with using landmarks to register (linear) individual scans for subsequent analyses or more sophisticated registration techniques, We next explored the use of interlandmark distances as indices of brain size, Twenty-seven landmarks were chosen from the midsagittal slice of 101 normal subjects. Interrater reliability estimates on a subset of the scans were excellent overall, Rotating to anterior-posterior commissure points was the best of the tested two-point registrations, although an average angular rotation was better. Reliability and validity for landmark-derived measures of size were excellent, Landmark-based analyses offer opportunities to explore shape and size questions, although they are not appropriate for addressing all questions. Under specific conditions, landmark data can be generated quickly and accurately.
引用
收藏
页码:145 / 154
页数:10
相关论文
共 26 条
[1]  
ANDREASEN NC, 1993, J NEUROPSYCH CLIN N, V5, P121
[2]  
Arndt S, 1994, Neuroimage, V1, P191, DOI 10.1006/nimg.1994.1004
[3]   ASSESSMENT OF DATA QUALITY - ERRORS OF MEASUREMENT AND ERRORS OF PROCESS [J].
ARNDT, S ;
WOOLSON, RW .
BIOMETRICAL JOURNAL, 1993, 35 (03) :315-324
[4]   EFFECTS OF ERRORS IN A MULTICENTER MEDICAL STUDY - PREVENTING MISINTERPRETED DATA [J].
ARNDT, S ;
TYRRELL, G ;
WOOLSON, RF ;
FLAUM, M ;
ANDREASEN, NC .
JOURNAL OF PSYCHIATRIC RESEARCH, 1994, 28 (05) :447-459
[5]  
Bookstein F. L., 1986, Statistical Science, V1, P181, DOI DOI 10.1214/SS/1177013696
[6]  
Bookstein F.L., 1991, Morphometric tools for landmark data
[7]  
Cohen J., 1988, Statistical Power Analysis for the Behavioral Sciences, V2
[8]   AUTOMATIC 3D INTERSUBJECT REGISTRATION OF MR VOLUMETRIC DATA IN STANDARDIZED TALAIRACH SPACE [J].
COLLINS, DL ;
NEELIN, P ;
PETERS, TM ;
EVANS, AC .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1994, 18 (02) :192-205
[9]  
DONGSHENG C, 1993, FORENSIC ANAL SKULL, P183
[10]  
Dunn G., 1989, Design and analysis of reliability studies: the statistical evaluation of measurement errors