Detection of stellate distortions in mammograms

被引:224
作者
Karssemeijer, N
teBrake, GM
机构
[1] University Hospital Nijmegen, Department of Radiology, Nijmegen, 6500 HB
关键词
D O I
10.1109/42.538938
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Malignant densities in mammograms have an irregular appearance and frequently are surrounded by a radiating pattern of linear spicules. In this paper a method is described to detect such stellate patterns, This method is based on statistical analysis of a map of pixel orientations. If an increase of pixels pointing to a region is found, this region is marked as suspicious, especially if such an increase is found in many directions, Orientations of the image intensity map are determined at each pixel using a multiscale approach. At a given scale, accurate line-based orientation estimates are obtained from the output of three-directional, second-order, Gaussian derivative operators. The orientation at the scale at which these operators have maximum response is selected. If a line-like structure is present at a given site, this method provides an estimate of the orientation of this structure, whereas in other cases the image noise will generate a random orientation, The pixel orientation map is used to construct two operators which are sensitive to radial patterns of straight lines. Combination of the output of these operators using a classifier allows for detection of stellate patterns. Different classification methods have been compared and results obtained on a common database are presented, Around 90% of the malignant cases were detected at rate of one false positive (FP) per image.
引用
收藏
页码:611 / 619
页数:9
相关论文
共 15 条
  • [11] AUTOMATED DETECTION AND CLASSIFICATION OF BREAST-TUMORS
    NG, SL
    BISCHOF, WF
    [J]. COMPUTERS AND BIOMEDICAL RESEARCH, 1992, 25 (03): : 218 - 237
  • [12] SAVAGE CJ, 1994, P 2 INT WORKSH DIG M, P405
  • [13] SUCKLING J, 1994, INT CONGR SER, V1069, P375
  • [14] VANDIJCK JAAM, 1993, CANCER, V72, P1933, DOI 10.1002/1097-0142(19930915)72:6<1933::AID-CNCR2820720623>3.0.CO
  • [15] 2-N