Aminohydroxylation and dihydroxylation of 4-aryl-1,2,5,6-tetrahydropyridines

被引：7

作者：

Chang, Meng-Yang ^{[1
]}

Lin, Chun-Yu

Wu, Tsun-Cheng

机构：

[1] Natl Univ Kaohsiung, Dept Appl Chem, Kaohsiung 811, Taiwan

[2] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 31期

关键词：

cerium ammonium nitrate; oxidative addition; hydrogenation; 4-aryl-1,2,5,6-tetrahydropyridines; aminohydroxylation; dihydroxylation;

D O I：

10.1016/j.tetlet.2006.05.174

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substituted 3-amino-4-aryl-4-liydi-oxypiperidines and 4-aryl-3.4-dihvdroxypiperidiiies are synthesized in the modest overall yields starting from the regio- and stereoselective trans-aminohydroxylation and dihydroxylation of 4-aryl-1,15.6-tetrahydropyridines via CAN-mediated oxidative addition and hydrogenation. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：5445 / 5449

页数：5

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