Olefin metathesis - recent applications in synthesis

被引:72
作者
Blechert, S [1 ]
机构
[1] Tech Univ Berlin, Inst Organ Chem, D-10623 Berlin, Germany
关键词
D O I
10.1351/pac199971081393
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Olefin methathesis allows for the catalytic cleavage and formation of C,C multiple bonds under mild conditions in the presence of various functional groups. Whereas ring closing metathesis has been widely used in the synthesis of cyclic olefins, less applications have been described for other metathesis types, namely cross and ring opening metathesis. The combination of these two reactions in domino processes and their application to the synthesis of complex natural products is described.
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页码:1393 / 1399
页数:7
相关论文
共 15 条
[1]  
Armstrong SK, 1998, J CHEM SOC PERK T 1, P371
[2]  
BRAEKMAN JC, 1987, Z NATURFORSCH C, V42, P627
[3]  
Brummer O, 1997, CHEM-EUR J, V3, P441
[4]   CONVULSANT ALKALOIDS FROM DIOSCOREA-DUMETORUM [J].
CORLEY, DG ;
TEMPESTA, MS ;
IWU, MM .
TETRAHEDRON LETTERS, 1985, 26 (13) :1615-1618
[5]   Recent advances in olefin metathesis and its application in organic synthesis [J].
Grubbs, RH ;
Chang, S .
TETRAHEDRON, 1998, 54 (18) :4413-4450
[6]   Selective ring-opening olefin metathesis of functionalized monosubstituted olefins [J].
Schneider, MF ;
Lucas, N ;
Velder, J ;
Blechert, S .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (03) :257-259
[7]   Increased ring closing metathesis activity of ruthenium-based olefin metathesis catalysts coordinated with imidazolin-2-ylidene ligands [J].
Scholl, M ;
Trnka, TM ;
Morgan, JP ;
Grubbs, RH .
TETRAHEDRON LETTERS, 1999, 40 (12) :2247-2250
[8]   SYNTHESIS OF MOLYBDENUM IMIDO ALKYLIDENE COMPLEXES AND SOME REACTIONS INVOLVING ACYCLIC OLEFINS [J].
SCHROCK, RR ;
MURDZEK, JS ;
BAZAN, GC ;
ROBBINS, J ;
DIMARE, M ;
OREGAN, M .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (10) :3875-3886
[9]  
Schuster M, 1997, ANGEW CHEM INT EDIT, V36, P2037
[10]   Ruthenium-catalysed cross metathesis binding of functionalized olefins to polystyrene resin via a novel allylsilyl linker suitable for electrophilic cleavage [J].
Schuster, M ;
Lucas, N ;
Blechert, S .
CHEMICAL COMMUNICATIONS, 1997, (09) :823-824