Epidemiology of environmental tobacco smoke exposure

被引:36
作者
Brownson, RC
Figgs, LW
Caisley, LE
机构
[1] St Louis Univ, Sch Publ Hlth, Salus Ctr, Dept Community Hlth, St Louis, MO 63104 USA
[2] St Louis Univ, Sch Publ Hlth, Salus Ctr, Prevent Res Ctr, St Louis, MO 63104 USA
基金
英国医学研究理事会;
关键词
environmental tobacco smoke; lung neoplasms; socioeconomic level; tobacco smoke pollution;
D O I
10.1038/sj.onc.1205809
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The health hazards due to exposure to environmental tobacco smoke (ETS) are increasingly established. ETS contains thousands of chemicals including 43 known carcinogens. One of the most important known health effects of ETS exposure is lung cancer in non-smokers, based on epidemiologic evidence and knowledge of the uptake and metabolism of ETS. Epidemiologic studies need to carefully take into account confounding and potential errors in exposure assessment. More research is needed to understand the genetic factors that influence ETS-induced lung cancer. Studies of the patterns of ETS exposure suggest higher rates of exposure in people employed as blue collar workers, in service occupations, earning lower incomes, and among the less educated. Certain racial/ethnic groups (e.g. Blacks, American Indians) may be at higher risk of ETS exposure. Despite substantial progress in protecting individuals from ETS exposure, additional efforts are needed in improving and enforcing policies to reduce exposure.
引用
收藏
页码:7341 / 7348
页数:8
相关论文
共 100 条
[1]  
AKIBA S, 1986, CANCER RES, V46, P4804
[2]  
[Anonymous], 1986, ENV TOB SMOK MEAS EX
[3]  
[Anonymous], 1986, HLTH CONS INV SMOK R
[4]  
Bartsch H, 2000, CANCER EPIDEM BIOMAR, V9, P3
[5]  
BAST RC, 2000, CANC MED
[6]   Environmental tobacco smoke, genetic susceptibility, and risk of lung cancer in never-smoking women [J].
Bennett, WP ;
Alavanja, MCR ;
Blomeke, B ;
Vähäkangas, KH ;
Castrén, K ;
Welsh, JA ;
Bowman, ED ;
Khan, MA ;
Flieder, DB ;
Harris, CC .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1999, 91 (23) :2009-2014
[7]   Cotinine as a biomarker of environmental tobacco smoke exposure [J].
Benowitz, NL .
EPIDEMIOLOGIC REVIEWS, 1996, 18 (02) :188-204
[8]   PUBLICATION BIAS AND PUBLIC-HEALTH POLICY ON ENVIRONMENTAL TOBACCO-SMOKE [J].
BERO, LA ;
GLANTZ, SA ;
RENNIE, D .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 272 (02) :133-136
[9]   Multicenter case-control study of exposure to environmental tobacco smoke and lung cancer in Europe [J].
Boffetta, P ;
Agudo, A ;
Ahrens, W ;
Benhamou, E ;
Benhamou, S ;
Darby, SC ;
Ferro, G ;
Fortes, C ;
Gonzalez, CA ;
Jöckel, KH ;
Krauss, M ;
Kreienbrock, L ;
Kreuzer, M ;
Mendes, A ;
Merletti, F ;
Nyberg, F ;
Pershagen, G ;
Poglabeln, H ;
Riboli, E ;
Schmid, G ;
Simonato, L ;
Trédaniel, J ;
Whitley, E ;
Wichmann, HE ;
Winck, C ;
Zambon, P ;
Saracci, R .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (19) :1440-1450
[10]   XRCC3 is required for efficient repair of chromosome breaks by homologous recombination [J].
Brenneman, MA ;
Weiss, AE ;
Nickoloff, JA ;
Chen, DJ .
MUTATION RESEARCH-DNA REPAIR, 2000, 459 (02) :89-97