Controlled rotation of biological micro- and nano-particles in microvortices

被引：39

作者：

Shelby, JP ^{[1
]}

Chiu, DT ^{[1
]}

机构：

[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA

来源：

LAB ON A CHIP | 2004年 / 4卷 / 03期

关键词：

D O I：

10.1039/b402479f

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Micrometer-sized re-circulating flows generated in a microfluidic system are used to drive the controlled rotation of biological particles of both micro- and nano-meter scale dimensions. This technique is independent of the intrinsic nature of the particle, and possesses the potential to rotate particles at high rates. We demonstrate in such microvortices the orientation control of single DNA molecules, and the axial rotation of biological cells in which the cellular contents were visibly affected by rotation.

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收藏

页码：168 / 170

页数：3

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