Plakins: Goliaths that link cell junctions and the cytoskeleton

被引：132

作者：

Jefferson, JJ

Leung, CL

Liem, RKH

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Pathol, New York, NY 10032 USA

[2] Columbia Univ Coll Phys & Surg, Dept Anat & Cell Biol, New York, NY 10032 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2004年 / 5卷 / 07期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrm1425

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Plakins comprise a family of proteins that crosslink cytoskeletal filaments and attach them to membrane-associated complexes at cell junctions. They were originally found associated with intermediate filaments and were believed to function primarily in maintaining epithelial tissue integrity. However, new plakins with unique isoforms that are enormous in size have been identified in the past few years. These new plakins have highlighted further functions in all the cytoskeletal networks, as well as in non-epithelial cells.

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页码：542 / 553

页数：12

相关论文

共 116 条

[41] Epithelial barrier function: assembly and structural features of the cornified cell envelope [J].

Kalinin, AE ;

Kajava, AV ;

Steinert, PM .

BIOESSAYS, 2002, 24 (09) :789-800

[42] An epidermal plakin that integrates actin and microtubule networks at cellular junctions [J].

Karakesisoglou, I ;

Yang, YM ;

Fuchs, E .

JOURNAL OF CELL BIOLOGY, 2000, 149 (01) :195-208

[43] Interaction of periplakin and envoplakin with intermediate filaments [J].

Karashima, T ;

Watt, FM .

JOURNAL OF CELL SCIENCE, 2002, 115 (24) :5027-5037

[44] Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma [J].

Keith, D ;

Armstrong, B ;

McKenna, KE ;

Purkis, PE ;

Green, KJ ;

Eady, RAJ ;

Leigh, IM ;

Hughes, AE .

HUMAN MOLECULAR GENETICS, 1999, 8 (01) :143-148

[45] ACF7: An essential integrator of microtubule dynamics [J].

Kodama, A ;

Karakesisoglou, L ;

Wong, E ;

Vaezi, A ;

Fuchs, E .

CELL, 2003, 115 (03) :343-354

[46] Calponin homology domains at a glance [J].

Korenbaum, E ;

Rivero, F .

JOURNAL OF CELL SCIENCE, 2002, 115 (18) :3543-3545

[47] A site-specific plectin mutation causes dominant epidermolysis bullosa simplex ogna:: Two identical de novo mutations [J].

Koss-Harnes, D ;

Hoyheim, B ;

Anton-Lamprecht, I ;

Gjesti, A ;

Jorgensen, PS ;

Jahnsen, FL ;

Olaisen, B ;

Wiche, G ;

Gedde-Dahl, T .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2002, 118 (01) :87-93

[48] Analysis of the interactions between BP180, BP230, plectin and the integrin α6β4 important for hemidesmosome assembly [J].

Koster, J ;

Geerts, D ;

Favre, B ;

Borradori, L ;

Sonnenberg, A .

JOURNAL OF CELL SCIENCE, 2003, 116 (02) :387-399

[49] MAKING A CONNECTION - DIRECT BINDING BETWEEN KERATIN INTERMEDIATE FILAMENTS AND DESMOSOMAL PROTEINS [J].

KOUKLIS, PD ;

HUTTON, E ;

FUCHS, E .

JOURNAL OF CELL BIOLOGY, 1994, 127 (04) :1049-1060

[50] short stop is allelic to kakapo, and encodes rod-like cytoskeletal-associated proteins required for axon extension [J].

Lee, S ;

Harris, KL ;

Whitington, PM ;

Kolodziej, PA .

JOURNAL OF NEUROSCIENCE, 2000, 20 (03) :1096-1108

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