Formal total synthesis of (+)-methynolide

被引：36

作者：

Cossy, J ^{[1
]}

Bauer, D ^{[1
]}

Bellosta, V ^{[1
]}

机构：

[1] Ecole Super Phys & Chim Ind Ville Paris, Chim Organ Lab, CNRS, F-75231 Paris 05, France

来源：

TETRAHEDRON | 2002年 / 58卷 / 29期

关键词：

macrolactone; metathesis; crotylboronate; Takai reaction; Sharpless kinetic resolution;

D O I：

10.1016/S0040-4020(02)00555-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A formal total synthesis of (+)-methynolide was achieved in 23 steps highlighted by a crotylboration, a ring-closing metathesis, a Sharpless kinetic resolution of an allylic alcohol and a Takai reaction. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：5909 / 5922

页数：14

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