Sex determination and sex reversal

被引：35

作者：

Camerino, Giovanna ^{[1
]}

Parma, Pietro ^{[1
]}

Radi, Orietta ^{[1
]}

Valentini, Stella ^{[1
]}

机构：

[1] Univ Pavia, Dipartimento Patol Umana & Ereditaria, I-27100 Pavia, Italy

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2006年 / 16卷 / 03期

关键词：

D O I：

10.1016/j.gde.2006.04.014

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Sex determination in mammals is based on a genetic cascade that controls the fate of the gonads. Gonads will then direct the establishment of phenotypic sex through the production of hormones. Different types of sex reversal are expected to occur if mutations disrupt one of the three steps of gonadal differentiation: formation of the gonadal primordia, sex determination, and testis or ovary development.

引用

页码：289 / 292

页数：4

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