Determination of enantiomeric excess and concentration of unprotected amino acids, amines, amino alcohols, and carboxylic acids by competitive binding assays with a chiral scandium complex

被引:134
作者
Mei, Xuefeng [1 ]
Wolf, Christian [1 ]
机构
[1] Georgetown Univ, Dept Chem, Washington, DC 20057 USA
关键词
D O I
10.1021/ja0636486
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A practical UV-vis sensing method for enantioselective microanalysis of unprotected amino acids, amines, amino alcohols, and carboxylic acids in aqueous solution has been developed. Both concentration and enantiomeric composition of a wide range of chiral substrates can be determined with high accuracy by two simple competitive binding assays using a scandium complex derived from 1,8-bis(3-(3′,5′-dimethylphenyl)-9-acridyl)naphthalene N,N′-dioxide. Copyright © 2006 American Chemical Society.
引用
收藏
页码:13326 / 13327
页数:2
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