Ceramic bioactivity and related biomimetic strategy

被引：119

作者：

Kim, HM ^{[1
]}

机构：

[1] Yonsei Univ, Sch Adv Mat Engn, Dept Ceram Engn, Seoul 120749, South Korea

来源：

CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE | 2003年 / 7卷 / 4-5期

关键词：

biomaterials; ceramics; bioactivity; calcium phosphate; apatite; in vitro; simulated body fluid; biomimetic process; tissue engineering;

D O I：

10.1016/j.cossms.2003.09.014

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Bioactivity a property displayed by ceramics such as Bioglass(R), hydroxyapatite and glass-ceramic A-W is a surface property, which provides a chemical integration of synthetic materials with living tissue. A core mechanism of bioactivity is the biomineralization of calcium phosphate nano-crystals on ceramics with specific compositions and structures, inspiring acellular and protein-free biomimetic strategies for bio-interactive materials with new physical, chemical and biological functions, e.g., bioactive surface functionalizations on tough metallic and ceramic materials, sot-gel derivation of bioactive ceramic-polymer nano-hybrids and textured biomimetic depositions of nano-calcium phosphate on polymer templates. This paper reviews these forms of bioactivity both in vivo and in vitro and considers perspectives in tissue engineering. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：289 / 299

页数：11

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