Comparison of the EUCAST-AFST broth dilution method with the CLSI reference broth dilution method (M38-A) for susceptibility testing of posaconazole and voriconazole against Aspergillus spp.

被引:39
作者
Chryssanthou, E. [1 ]
Cuenca-Estrella, M.
机构
[1] Karolinska Univ Hosp, Dept Clin Microbiol, SE-14186 Stockholm, Sweden
[2] Inst Salud Carlos III, Ctr Nacl Microbiol, Serv Micol, Majadahonda, Spain
关键词
Aspergillus spp; broth dilutions; posaconazole; susceptibility testing; voriconazole;
D O I
10.1111/j.1469-0691.2006.01419.x
中图分类号
R51 [传染病];
学科分类号
100401 [流行病与卫生统计学];
摘要
The susceptibilities of 40 clinical isolates of Aspergillus spp. (Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, Aspergillus terreus) were determined for posaconazole and voriconazole by the CLSI M38-A and EUCAST-AFST broth dilution methods. Where a discrepancy was observed between the methods, the EUCAST method tended to give higher MIC values. Overall, the level of agreement was 92.5% and the intra-class correlation coefficient was > 0.90.
引用
收藏
页码:901 / 904
页数:4
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