Design of new chiral tetraol host compounds, trans-1,4-bis[3-(o-chlorophenyl)-3-hydroxy-3-phenylprop-1-ynyl]-1,4-dihydroxy-cyclohexa-2,5-diene and its tetrahalogeno derivatives

The title chiral tetraol host and its 2,3,5,6-tetrachloro and -tetrabromo derivatives have been prepared by the addition of the lithium acetylide derived from (R)-(-)-1-(o-chlorophenyl)-1-hydroxy-1-phenylprop-2-yne to benzoquinone, chloranil and bromanil, respectively and by complexation with these chiral host compounds, various kinds of rac-guest compounds have been resolved very efficiently.