New integron-associated gene cassette encoding a trimethoprim-resistant dfrB-type dihydrofolate reductase

被引：21

作者：

Levings, Renee S.

Lightfoot, Diane

Elbourne, Liam D. H.

Djordjevic, Steven P.

Hall, Ruth M.

机构：

[1] Univ Sydney, Sch Mol & Microbial Biosci, Sydney, NSW 2006, Australia

[2] Elizabeth Macarthur Agr Inst, New S Wales Dept Primary Ind, Microbiol & Immunol Sect, Camden, NSW 2570, Australia

[3] Univ Wollongong, Dept Biol Sci, Wollongong, NSW 2522, Australia

[4] Univ Melbourne, Microbiol Diagnost Unit, Publ Hlth Lab, Dept Microbiol & Immunol, Melbourne, Vic 3010, Australia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 08期

关键词：

D O I：

10.1128/AAC.00449-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class I integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim.

引用

页码：2863 / 2865

页数：3

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