Crystal-to-crystal transformations of a microporous metal organic laminated framework triggered by guest exchange, dehydration and readsorption

Single crystals of a neutral, microporous, laminated metal-organic framework (MOF) [Fe(pydc)(4,4'-bipy)].H2O (1.H2O) (H(2)pydc = 2,5-dicarboxypyridine, 4,4'-bipy = 4,4'-bipyridine) were generated by hydrothermal synthesis, and its crystal structure was determined. 1.H2O retains the framework robustness to ca. 370 degreesC and is insoluble in common organic solvents. By soaking in MeOH and EtOH solutions, 1.H2O was transformed directly from the parent single crystals into single crystals of 1.MeOH or 1.EtOH, respectively. Meanwhile, 1.H2O shrank to the guest-free framework 1(h) or 1(v), respectively, under appropriate heating (up to 160 degreesC in N-2) or vacuum treatment (10 mmHg) at room temperature. Compared to that of 1.H2O, the unit-cell volume of 1.EtOH slightly increases by 2.9%, whereas those of 1(h) or 1(v) are reduced by 8.2 and 6.6%, respectively. The anhydrous 1(v) was found to be highly chemically reactive, taking up ethanol vapor to furnish the solvated crystal structure of an 'expanded' framework 1.EtOH. In a mixture of ethanol-DMF or ethanol-benzene, a selective exchange process was observed, with only ethanol molecules exchanged into the structure due to the limited free size of the channels in the framework of 1. All the transformed crystals have also been characterized by X-ray single-crystal diffraction to understand the crystal-to-crystal transformation, which have different free volumes (6.5-20.4%).