Modeling of asthma, COPD and cystic fibrosis in sheep

被引：49

作者：

Abraham, William M. ^{[1
]}

机构：

[1] Mt Sinai Med Ctr, Dept Res, Miami Beach, FL 33140 USA

来源：

PULMONARY PHARMACOLOGY & THERAPEUTICS | 2008年 / 21卷 / 05期

关键词：

Animal models; Bronchoconstriction; Mucus clearance; Airway inflammation;

D O I：

10.1016/j.pupt.2008.01.010

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Sheep naturally allergic to Ascaris suum antigen have been used to study the pathophysiology of asthma and more recently allergic rhinitis, chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The utility of the model as it relates to the study of these diseases is discussed. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：743 / 754

页数：12