[1] Newcastle Univ, Sch Clin Med Sci, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
[2] Univ Southampton, Geriatr Med Grp, Southampton, Hants, England
[3] St Helier Hosp, Dept Rheumatol, Carshalton SM5 1AA, Surrey, England
[4] Univ Nottingham Hosp, Queens Med Ctr, Dept Hlth Care Elderly, Nottingham NG7 2UH, England
[5] Univ Utrecht, Utrecht, Netherlands
[6] Procter & Gamble Pharmaceut, Utrecht, Netherlands