Caenorhabditis elegans:: a model genetic host to study Pseudomonas aeruginosa pathogenesis

被引：119

作者：

Tan, MW

Ausubel, FM

机构：

[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Biol Mol, Boston, MA 02114 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2000年 / 3卷 / 01期

关键词：

D O I：

10.1016/S1369-5274(99)00047-8

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In the past year, a Caenorhabditis elegans-Pseudomonas aeruginosa pathogenesis model has been developed to facilitate the systematic dissection of both host and pathogen genes involved in pathogenic interactions. Analysis of the P. aeruginosa-C. elegans interaction should shed light on the larger question of how organisms interact at the molecular level in antagonistic relationships.

引用

页码：29 / 34

页数：6

共 40 条

[1] EFFECT OF BACTERIA ON DISPERSAL OF CAENORHABDITIS-ELEGANS (RHABDITIDAE)
ANDREW, PA
NICHOLAS, WL
[J]. NEMATOLOGICA, 1976, 22 (04): : 451 - 461
[2] Antimicrobial peptides in insects; structure and function
Bulet, P
Hetru, C
Dimarcq, JL
Hoffmann, D
[J]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 1999, 23 (4-5) : 329 - 344
[3] Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa
Darby, C
Cosma, CL
Thomas, JH
Manoil, C
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (26) : 15202 - 15207
[4] Drosophila immune responses as models for human immunity
Dushay, MS
Eldon, ED
[J]. AMERICAN JOURNAL OF HUMAN GENETICS, 1998, 62 (01) : 10 - 14
[5] Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila
Dushay, MS
Asling, B
Hultmark, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (19) : 10343 - 10347
[6] Common themes in microbial pathogenicity revisited
Finlay, BB
Falkow, S
[J]. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1997, 61 (02) : 136 - +
[7] Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A
Xu, SQ
Montgomery, MK
Kostas, SA
Driver, SE
Mello, CC
[J]. NATURE, 1998, 391 (6669) : 806 - 811
[8] The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
Fukushige, T
Hawkins, MG
McGhee, JD
[J]. DEVELOPMENTAL BIOLOGY, 1998, 198 (02) : 286 - 302
[9] Use of Arabidopsis for genetic dissection of plant defense responses
Glazebrook, J
Rogers, EE
Ausubel, FM
[J]. ANNUAL REVIEW OF GENETICS, 1997, 31 : 547 - 569
[10] Genes controlling expression of defense responses in Arabidopsis
Glazebrook, J
[J]. CURRENT OPINION IN PLANT BIOLOGY, 1999, 2 (04) : 280 - 286

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