Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia

被引:3082
作者
Chen, Liang-Kung [1 ]
Liu, Li-Kuo [1 ]
Woo, Jean [2 ]
Assantachai, Prasert [3 ]
Auyeung, Tung-Wai [2 ]
Bahyah, Kamaruzzaman Shahrul [4 ]
Chou, Ming-Yueh [5 ]
Chen, Liang-Yu [1 ]
Hsu, Pi-Shan [6 ]
Krairit, Orapitchaya [7 ]
Lee, Jenny S. W. [2 ]
Lee, Wei-Ju [8 ]
Lee, Yunhwan [9 ]
Liang, Chih-Kuang [5 ]
Limpawattana, Panita [10 ]
Lin, Chu-Sheng [11 ]
Peng, Li-Ning [1 ]
Satake, Shosuke [12 ]
Suzuki, Takao [13 ]
Won, Chang Won [14 ]
Wu, Chih-Hsing [15 ]
Wu, Si-Nan [16 ]
Zhang, Teimei [16 ]
Zeng, Ping [16 ]
Akishita, Masahiro [17 ]
Arai, Hidenori [18 ]
机构
[1] Taipei Vet Gen Hosp, Ctr Geriatr & Gerontol, Taipei, Taiwan
[2] Chinese Univ Hong Kong, SH Ho Ctr Gerontol & Geriatr, Hong Kong, Hong Kong, Peoples R China
[3] Mahidol Univ, Siriraj Hosp, Dept Prevent & Social Med, Bangkok 10700, Thailand
[4] Univ Malaya, Dept Med, Kuala Lumpur, Malaysia
[5] Kaohsiung Vet Gen Hosp, Geriatr Med Ctr, Kaohsiung, Taiwan
[6] Minist Hlth & Welf, Taichung Hosp, Dept Family Med, Taichung, Taiwan
[7] Mahidol Univ, Ramathibodi Hosp, Dept Internal Med, Bangkok 10700, Thailand
[8] Taipei Vet Gen Hosp, Yuanshan Branch, Dept Family Med, I Land, Taiwan
[9] Ajou Univ, Sch Med, Dept Prevent Med & Publ Hlth, Suwon 441749, South Korea
[10] Khon Kaen Univ, Fac Med, Dept Med, Khon Kaen, Thailand
[11] Taichung Vet Gen Hosp, Ctr Geriatr & Gerontol, Taichung, Taiwan
[12] Natl Ctr Geriatr & Gerontol, Dept Comprehens Geriatr Med, Obu, Japan
[13] Natl Ctr Geriatr & Gerontol, Res Inst, Obu, Japan
[14] Kyung Hee Univ, Sch Med, Dept Family Med, Seoul, South Korea
[15] Natl Cheng Kung Univ, Hosp & Coll Med, Dept Family Med, Tainan 70101, Taiwan
[16] Minist Hlth, Beijing Hosp, Beijing Inst Geriatr, Beijing, Peoples R China
[17] Kyoto Univ, Grad Sch Med, Dept Human Hlth Sci, Kyoto, Japan
[18] Univ Tokyo, Grad Sch Med, Dept Geriatr Med, Tokyo, Japan
关键词
Sarcopenia; frailty; muscle mass; muscle quality; muscle strength; physical performance; BIOELECTRICAL-IMPEDANCE ANALYSIS; GROWTH-HORMONE REPLACEMENT; SKELETAL-MUSCLE MASS; WOMEN AGED 75; PHYSICAL PERFORMANCE; BODY-COMPOSITION; OLDER-ADULTS; CHINESE MEN; ELDERLY-PEOPLE; STRENGTH;
D O I
10.1016/j.jamda.2013.11.025
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Sarcopenia, a newly recognized geriatric syndrome, is characterized by age-related decline of skeletal muscle plus low muscle strength and/ or physical performance. Previous studies have confirmed the association of sarcopenia and adverse health outcomes, such as falls, disability, hospital admission, long term care placement, poorer quality of life, and mortality, which denotes the importance of sarcopenia in the health care for older people. Despite the clinical significance of sarcopenia, the operational definition of sarcopenia and standardized intervention programs are still lacking. It is generally agreed by the different working groups for sarcopenia in the world that sarcopenia should be defined through a combined approach of muscle mass and muscle quality, however, selecting appropriate diagnostic cutoff values for all the measurements in Asian populations is challenging. Asia is a rapidly aging region with a huge population, so the impact of sarcopenia to this region is estimated to be huge as well. Asian Working Group for Sarcopenia (AWGS) aimed to promote sarcopenia research in Asia, and we collected the best available evidences of sarcopenia researches from Asian countries to establish the consensus for sarcopenia diagnosis. AWGS has agreed with the previous reports that sarcopenia should be described as low muscle mass plus low muscle strength and/or low physical performance, and we also recommend outcome indicators for further researches, as well as the conditions that sarcopenia should be assessed. In addition to sarcopenia screening for community-dwelling older people, AWGS recommends sarcopenia assessment in certain clinical conditions and healthcare settings to facilitate implementing sarcopenia in clinical practice. Moreover, we also recommend cutoff values for muscle mass measurements (7.0 kg/m(2) for men and 5.4 kg/m(2) for women by using dual X-ray absorptiometry, and 7.0 kg/m(2) for men and 5.7 kg/m(2) for women by using bioimpedance analysis), handgrip strength (<26 kg for men and <18 kg for women), and usual gait speed (<0.8 m/s). However, a number of challenges remained to be solved in the future. Asia is made up of a great number of ethnicities. The majority of currently available studies have been published from eastern Asia, therefore, more studies of sarcopenia in south, southeastern, and western Asia should be promoted. On the other hand, most Asian studies have been conducted in a cross-sectional design and few longitudinal studies have not necessarily collected the commonly used outcome indicators as other reports from Western countries. Nevertheless, the AWGS consensus report is believed to promote more Asian sarcopenia research, and most important of all, to focus on sarcopenia intervention studies and the implementation of sarcopenia in clinical practice to improve health care outcomes of older people in the communities and the healthcare settings in Asia. (C) 2014 -American Medical Directors Association, Inc. All rights reserved.
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页码:95 / 101
页数:7
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