In vivo measurement of the local optical properties of tissue by use of differential path-length spectroscopy

被引：131

作者：

Amelink, A

Sterenborg, HJCM

Bard, MPL

Burgers, SA

机构：

[1] Erasmus Med Ctr, Dept Radiat Oncol, NL-3008 AE Rotterdam, Netherlands

[2] Erasmus Sch Ctr, Dept Pulm Dis, NL-3008 AE Rotterdam, Netherlands

来源：

OPTICS LETTERS | 2004年 / 29卷 / 10期

关键词：

D O I：

10.1364/OL.29.001087

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We demonstrate the capability of differential path-length spectroscopy (DPS) to determine the local optical properties of tissue in vivo. DPS measurements on bronchial mucosa are analyzed and yield information on the local blood oxygenation, blood content, average microvessel diameter, and wavelength dependence of the reduced scattering coefficient. Our data collected to date show that cancerous bronchial mucosa has a lower capillary oxygenation and a larger average capillary diameter than normal bronchial mucosa. (C) 2004 Optical Society of America

引用

页码：1087 / 1089

页数：3

共 22 条

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