New multi-coupling benzylic zinc reagents for the preparation of flexible aromatic compounds

被引：30

作者：

Rottlander, M ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] UNIV MARBURG,FACHBEREICH CHEM,D-35032 MARBURG,GERMANY

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(97)00187-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The benzylic zinc reagents 3a-c bearing a triflate group in o-, m- or p-position are new efficient multi-coupling reagents reacting stepwise with an aryl iodide (Ar-1-I) and an arylzinc bromide ((ArZnBr)-Zn-2) in the presence of the appropriate palladium catalyst and the suitable phosphine ligand leading to polyfunctional flexible aromatic products of type 5. This methodology is appropriate for applications in combinatorial chemistry. (C) 1997 Elsevier Science Ltd.

引用

页码：1749 / 1752

页数：4

共 26 条

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