Pharmacological prevention of Parkinson disease in Drosophila

被引：224

作者：

Auluck, PK ^{[1
]}

Bonini, NM

机构：

[1] Univ Penn, Dept Neurosci, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Biol, Philadelphia, PA 19104 USA

[3] Univ Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA

[4] Univ Penn, Sch Med, Philadelphia, PA 19104 USA

来源：

NATURE MEDICINE | 2002年 / 8卷 / 11期

关键词：

D O I：

10.1038/nm1102-1185

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1185 / 1186

页数：2

共 10 条

[1] Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
Auluck, PK
Chan, HYE
Trojanowski, JQ
Lee, VMY
Bonini, NM
[J]. SCIENCE, 2002, 295 (5556) : 865 - 868
[2] A Drosophila model of Parkinson's disease
Feany, MB
Bender, WW
[J]. NATURE, 2000, 404 (6776) : 394 - 398
[3] Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
Krüger, R
Kuhn, W
Müller, T
Woitalla, D
Graeber, M
Kösel, S
Przuntek, H
Epplen, JT
Schöls, L
Riess, O
[J]. NATURE GENETICS, 1998, 18 (02) : 106 - 108
[4] Parkinson's disease - Second of two parts
Lang, AE
Lozano, AM
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (16) : 1130 - 1143
[5] Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
Polymeropoulos, MH
Lavedan, C
Leroy, E
Ide, SE
Dehejia, A
Dutra, A
Pike, B
Root, H
Rubenstein, J
Boyer, R
Stenroos, ES
Chandrasekharappa, S
Athanassiadou, A
Papapetropoulos, T
Johnson, WG
Lazzarini, AM
Duvoisin, RC
DiIorio, G
Golbe, LI
Nussbaum, RL
[J]. SCIENCE, 1997, 276 (5321) : 2045 - 2047
[6] Hsp90 as a capacitor for morphological evolution
Rutherford, SL
Lindquist, S
[J]. NATURE, 1998, 396 (6709) : 336 - 342
[7] Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease
Sittler, A
Lurz, R
Lueder, G
Priller, J
Hayer-Hartl, MK
Hartl, FU
Lehrach, H
Wanker, EE
[J]. HUMAN MOLECULAR GENETICS, 2001, 10 (12) : 1307 - 1315
[8] alpha-synuclein in Lewy bodies
Spillantini, MG
Schmidt, ML
Lee, VMY
Trojanowski, JQ
Jakes, R
Goedert, M
[J]. NATURE, 1997, 388 (6645) : 839 - 840
[9] INHIBITION OF HEAT-SHOCK PROTEIN HSP90-PP60(V-SRC) HETEROPROTEIN COMPLEX-FORMATION BY BENZOQUINONE ANSAMYCINS - ESSENTIAL ROLE FOR STRESS PROTEINS IN ONCOGENIC TRANSFORMATION
WHITESELL, L
MIMNAUGH, EG
DECOSTA, B
MYERS, CE
NECKERS, LM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (18) : 8324 - 8328
[10] Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
Zou, JY
Guo, YL
Guettouche, T
Smith, DF
Voellmy, R
[J]. CELL, 1998, 94 (04) : 471 - 480

← 1 →