A solid supported synthesis of thiol esters

被引：24

作者：

Adamczyk, M

Fishpaugh, JR

机构：

[1] Abbott Laboratories, Abbott Park, IL 60064, 100 Abbott Park Road

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 25期

关键词：

D O I：

10.1016/0040-4039(96)00831-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of thiol esters was conveniently prepared from thiols and carboxylic acids using ethyl 3-(dimethylamino)propyl carbodiimide (EDAC) on a solid support in good to high yield for primary and aryl thiol esters with lower yields for secondary and tertiary thiol esters. Copyright (C) 1996 Elsevier Science Ltd.

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收藏

页码：4305 / 4308

页数：4

相关论文

共 35 条

[1] AN EASY PREPARATION OF HAPTEN ACTIVE ESTERS VIA SOLID SUPPORTED EDAC [J].

ADAMCZYK, M ;

FISHPAUGH, JR ;

MATTINGLY, PG .

TETRAHEDRON LETTERS, 1995, 36 (46) :8345-8346

[2] COBALT(II) CHLORIDE CATALYZED COUPLING OF THIOLS AND ANHYDRIDES - A NEW AND EFFICIENT SYNTHESIS OF THIOL ESTERS [J].

AHMAD, S ;

IQBAL, J .

TETRAHEDRON LETTERS, 1986, 27 (32) :3791-3794

[3] SYNTHESIS AND EVALUATION OF NEW ELASTASE INHIBITORS .1. 1,1-DIOXOCEPHEM-4-THIOLESTERS [J].

ALPEGIANI, M ;

BAICI, A ;

BISSOLINO, P ;

CARMINATI, P ;

CASSINELLI, G ;

DELNERO, S ;

FRANCESCHI, G ;

OREZZI, P ;

PERRONE, E ;

RIZZO, V ;

SACCHI, N .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1992, 27 (09) :875-890

[4]

ANAUNZIATA R, 1995, TETRAHEDRON LETT, V36, P613

[5] CHEMICAL LIGATION OF CYSTEINE-CONTAINING PEPTIDES - SYNTHESIS OF A 22-KDA TETHERED DIMER OF HIV-1 PROTEASE [J].

BACA, M ;

MUIR, TW ;

SCHNOLZER, M ;

KENT, SBH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (07) :1881-1887

[6]

BENZ H, 1994, SYNTHESIS-STUTTGART, P337

[7]

BOLASCO F, 1980, Patent No. 4242354

[8] EFFICIENT PREPARATION OF POLYFUNCTIONAL ALPHA-DIKETONES FROM CARBOXYLIC-ACIDS [J].

CONROW, R ;

PORTOGHESE, PS .

JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (06) :938-940

[9] TOTAL SYNTHESIS OF LACTACYSTIN [J].

COREY, EJ ;

REICHARD, GA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (26) :10677-10678

[10] AMIDE BOND FORMATION VIA PENTAFLUOROTHIOPHENYL ACTIVE ESTERS [J].

DAVIS, AP ;

WALSH, JJ .

TETRAHEDRON LETTERS, 1994, 35 (27) :4865-4868

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