AN EASY PREPARATION OF HAPTEN ACTIVE ESTERS VIA SOLID SUPPORTED EDAC

被引：37

作者：

ADAMCZYK, M

FISHPAUGH, JR

MATTINGLY, PG

机构：

[1] Abbott Laboratories, Abbott Park, IL 60064, 100 Abbott Park Road

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 46期

关键词：

D O I：

10.1016/0040-4039(95)01761-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bioconjugates are preferably prepared by reacting an active ester of the hapten of interest to the protein. Preparation of active esters with solid supported EDAC and N-hydroxysuccinimide or pentafluorophenol affords active esters in excellent yield and purity.

引用

页码：8345 / 8346

页数：2

共 9 条

[1]

ADAMCZYK M, UNPUB

[2] PEPTIDE-SYNTHESIS .10. USE OF PENTAFLUOROPHENYL ESTERS OF FLUORENYL METHOXYCARBONYLAMINO ACIDS IN SOLID-PHASE PEPTIDE-SYNTHESIS [J].