Mapping transcranial magnetic stimulation (TMS) fields in vivo with MRI

被引:105
作者
Bohning, DE
Pecheny, AP
Epstein, CM
Speer, AM
Vincent, DJ
Dannels, W
George, MS
机构
[1] MED UNIV S CAROLINA, DEPT PSYCHIAT, CHARLESTON, SC 29425 USA
[2] MED UNIV S CAROLINA, DEPT NEUROL, CHARLESTON, SC 29425 USA
[3] EMORY UNIV, DEPT NEUROL, ATLANTA, GA 30322 USA
[4] PICKER INT, CLEVELAND, OH USA
关键词
brain; human; magnetic field maps; MRI; MR phase mapping; TMS coils;
D O I
10.1097/00001756-199707280-00023
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
TRANSCRANIAL magnetic stimulation (TMS) is a noninvasive technique for investigating brain function that uses pulsed magnetic fields created by special coils to induce localized neuronal depolarization. Despite the technique's expanding application, the exact magnetic field produced by TMS coils have never been directly measured in human subjects. Using a standard 1.5T MR scanner and TMS coils constructed from non magnetic materials, we have obtained 3D maps of the magnetic field created by TMS coils in human volunteers. Further, we mapped the combined field of two coils and demonstrated that combinations of coils might be used to focus the magnetic field to achieve improved stimulation patterns and, perhaps, reach areas out of reach of single coils.
引用
收藏
页码:2535 / 2538
页数:4
相关论文
共 19 条
[1]  
BARKER AT, 1985, LANCET, V1, P1106
[2]  
BARKER AT, 1987, NEUROSURGERY, V20, P100
[3]   RAPID REVERSIBLE MODULATION OF HUMAN MOTOR OUTPUTS AFTER TRANSIENT DEAFFERENTATION OF THE FOREARM - A STUDY WITH TRANSCRANIAL MAGNETIC STIMULATION [J].
BRASILNETO, JP ;
COHEN, LG ;
PASCUALLEONE, A ;
JABIR, FK ;
WALL, RT ;
HALLETT, M .
NEUROLOGY, 1992, 42 (07) :1302-1306
[4]   LOCALIZING THE SITE OF MAGNETIC BRAIN-STIMULATION IN HUMANS [J].
EPSTEIN, CM ;
SCHWARTZBERG, DG ;
DAVEY, KR ;
SUDDERTH, DB .
NEUROLOGY, 1990, 40 (04) :666-670
[5]  
GEDDES LA, 1987, NEUROSURGERY, V20, P94
[6]  
George MS, 1996, J NEUROPSYCH CLIN N, V8, P373
[7]   DAILY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (RTMS) IMPROVES MOOD IN DEPRESSION [J].
GEORGE, MS ;
WASSERMANN, EM ;
WILLIAMS, WA ;
CALLAHAN, A ;
KETTER, TA ;
BASSER, P ;
HALLETT, M ;
POST, RM .
NEUROREPORT, 1995, 6 (14) :1853-1856
[8]  
GEORGE MS, 1996, AM PSYCHIAT ASS NEW, V768, P280
[9]  
HALLETT M, 1991, ELECTROEN CLIN NEURO, P76
[10]   A NEW 2-DIMENSIONAL PHASE UNWRAPPING ALGORITHM FOR MRI IMAGES [J].
HEDLEY, M ;
ROSENFELD, D .
MAGNETIC RESONANCE IN MEDICINE, 1992, 24 (01) :177-181