Catalytic Enantioselective Meerwein-Eschenmoser Claisen Rearrangement: Asymmetric Synthesis of Allyl Oxindoles

被引：149

作者：

Linton, Elizabeth C. ^{[1
]}

Kozlowski, Marisa C. ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Roy & Diana Vagelos Labs, Philadelphia, PA 19104 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 48期

关键词：

D O I：

10.1021/ja807026z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first catalytic, enantioselective Meerwein-Eschenmoser Claisen rearrangement has been achieved, Palladium(II) BINAP or phosphinooxazoline catalysts were employed to generate oxindole products with 100% conversion and up to 92% ee.

引用

页码：16162 / +

页数：3

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