Medical progress - Hypocapnia

被引:227
作者
Laffey, JG
Kavanagh, BP
机构
[1] Hosp Sick Children, Dept Crit Care Med, Toronto, ON M5G 1X8, Canada
[2] Hosp Sick Children, Lung Biol Program, Toronto, ON M5G 1X8, Canada
[3] Hosp Sick Children, Res Inst, Toronto, ON M5G 1X8, Canada
[4] Univ Toronto, Program Crit Care Med, Toronto, ON, Canada
[5] Univ Coll Dublin, Conway Inst Biomol & Biomed Res, Dept Physiol, Dublin 2, Ireland
[6] St Vincents Univ Hosp, Dept Anaesthesia & Intens Care, Dublin, Ireland
关键词
D O I
10.1056/NEJMra012457
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hypocapnia is neither a benign clinical entity nor an epiphenomenon. On the contrary, increasing evidence suggests that hypocapnia appears to induce substantial adverse physiological and medical effects. Thus, the decision to institute hypocapnia for therapeutic purposes should be undertaken only after careful consideration of the risks and benefits and should in general be limited to emergency management of life-threatening increases in intracranial pressure or pulmonary-vascular resistance. The risk of accidental hypocapnia should be recognized and measures taken to prevent it. Prophylactic induction of hypocapnia currently has no clinical role.
引用
收藏
页码:43 / 53
页数:11
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