The CeCl3•7H2O-NaI system as promoter in the synthesis of functionalized trisubstituted alkenes via Knoevenagel condensation

被引：46

作者：

Bartoli, Giuseppe

Beleggia, Romina

Giuli, Sandra

Giuliani, Arianna

Marcantoni, Enrico

Massaccesi, Massimo

Paoletti, Melissa

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, MC, Italy

[2] Univ Bologna, Dipartimento Chim Organ A Mangini, I-40136 Bologna, Italy

[3] Univ Foggia, Dipartimento Sci Alimenti, I-71100 Foggia, Italy

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 37期

关键词：

D O I：

10.1016/j.tetlet.2006.07.031

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The arylidene malonates with two different geminal carboxylate functions, a suitable class of substrates of several synthetic and pharmacological studies, are easily available through Knoevenagel condensation of ethyl tert-butyl malonate and different aromatic aldehydes. The results have increased the potentialities of CeCl3 center dot H-2-O-NaI system as a type of water-tolerant green Lewis acid promoter for carbon-carbon bond forming procedures. (c) 2006 Elsevier Ltd. All rights reserved.

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页码：6501 / 6504

页数：4

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