Study on Sensitization from Reactive Oxygen Species for Electrochemiluminescence of Luminol in Neutral Medium

被引：61

作者：

Chu, Haihong ^{[1
]}

Guo, Wenying ^{[1
]}

Di, Junwei ^{[1
]}

Wu, Ying ^{[1
]}

Tu, Yifeng ^{[1
]}

机构：

[1] Suzhou Univ, Dept Chem, Inst Analyt Chem, Suzhou 215123, Peoples R China

来源：

ELECTROANALYSIS | 2009年 / 21卷 / 14期

基金：

中国国家自然科学基金;

关键词：

Luminescence; Luminol; Sensitization; Reactive oxygen species; Neutral medium; Bioorganic chemistry; SELF-ASSEMBLED MONOLAYERS; ELECTROGENERATED CHEMILUMINESCENCE; SUPEROXIDE-DISMUTASE; GRAPHITE ELECTRODE; ALKALINE-SOLUTION; AQUEOUS-SOLUTION; GOLD ELECTRODE; SENSOR; OXIDE; GLUTATHIONE;

D O I：

10.1002/elan.200804580

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this paper, the sensitization on electrochemiluminescent (ECL) reaction of luminol from reactive oxygen species (ROSs) in neutral medium was studied. The powerful sensitization from ROSs even related with organics and organisms were examined under selected conditions which were suitable for biochemical analysis. The results indicated that whether the enhancers were dissolved in solutions or immobilized on the surface of conventional electrodes, stronger ECL intensity of luminol could be obtained. Enhanced ECL helped to provide groundwork for the detection of biomolecules for which would further enhance or quench the ECL signals. The technique may provide new means in a variety of fields such as clinical diagnostics, immunological analysis and environmental monitoring due to its simplicity and high efficiency.

引用

页码：1630 / 1635

页数：6

共 39 条

[1] Radical scavenging activity of various extracts and fractions of sweet orange-peel (Citrus sinensis) [J].

Anagnostopoulou, MA ;

Kefalas, P ;

Papageorgiou, VP ;

Assimopoulou, AN ;

Boskou, D .

FOOD CHEMISTRY, 2006, 94 (01) :19-25

[2] A new paradigm:: Manganese superoxide dismutase influences the production of H2O2 in cells and thereby their biological state [J].

Buettner, Garry R. ;

Ng, Chin F. ;

Wang, Min ;

Rodgers, V. G. J. ;

Schafer, Freya Q. .

FREE RADICAL BIOLOGY AND MEDICINE, 2006, 41 (08) :1338-1350

[3] Evaluation of radical scavenging properties of several plants, fresh or from a herbalist's, using a superoxide dismutase biosensor [J].

Campanella, L ;

Favero, G ;

Persi, L ;

Tomassetti, M .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2001, 24 (5-6) :1055-1064

[4] Highly sensitive electrogenerated chemiluminescence (ECL) method for famotidine with pre-anodizing technique to improve ECL reaction microenvironment at graphite electrode surface [J].

Chang, Z ;

Zheng, XW .

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2006, 587 (01) :161-168

[5] Multichannel electrochemiluminescence of luminol in neutral and alkaline aqueous solutions on a gold nanoparticle self-assembled electrode [J].

Cui, H ;

Xu, Y ;

Zhang, ZF .

ANALYTICAL CHEMISTRY, 2004, 76 (14) :4002-4010

[6] Electrochemiluminescence of luminol in alkaline solution at a paraffin-impregnated graphite electrode [J].

Cui, H ;

Zou, GZ ;

Lin, XQ .

ANALYTICAL CHEMISTRY, 2003, 75 (02) :324-331

[7] Examination of free radical metabolism and antioxidant defence system elements in patients with obsessive-compulsive disorder [J].

Ersan, Serpil ;

Bakir, Sevtap ;

Ersan, E. Erdal ;

Dogan, Orhan .

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2006, 30 (06) :1039-1042

[8] Recent applications of electrogenerated chemiluminescence in chemical analysis [J].

Fähnrich, KA ;

Pravda, M ;

Guilbault, GG .

TALANTA, 2001, 54 (04) :531-559

[9] SENSITIVE DETECTION OF BIOTOXOIDS AND BACTERIAL-SPORES USING AN IMMUNOMAGNETIC ELECTROCHEMILUMINESCENCE SENSOR [J].

GATTOMENKING, DL ;

YU, H ;

BRUNO, JG ;

GOODE, MT ;

MILLER, M ;

ZULICH, AW .

BIOSENSORS & BIOELECTRONICS, 1995, 10 (6-7) :501-507

[10] Inhibition of superoxide dismutase, Vitamin C and glutathione on chemiluminescence produced by luminol and the mixture of sulfite and bisulfite [J].

Geng, H ;

Meng, ZQ .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2006, 64 (01) :87-92

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