Asymmetric expression of antivin/lefty1 in the early chick embryo

被引：32

作者：

Ishimaru, Y

Yoshioka, H

Tao, H

Thisse, B

Thisse, C

Wright, CVE

Hamada, H

Ohuchi, H

Noji, S

机构：

[1] Univ Tokushima, Fac Engn, Dept Biol Sci & Technol, Tokushima 7708506, Japan

[2] ULP, INSERM, CNRS, Inst Genet & Biol Mol & Cellulaire, F-67404 Illkirch Graffenstaden, France

[3] Vanderbilt Univ, Sch Med, Dept Cell Biol, Nashville, TN 37232 USA

[4] Osaka Univ, Inst Mol & Cellular Biol, Suita, Osaka 5650871, Japan

[5] Japan Sci & Technol Corp, CREST, Tokyo, Japan

[6] Kyoto Univ, Grad Sch Pharmaceut Sci, Dept Biochem Genet, Sakyo Ku, Kyoto 6068501, Japan

来源：

MECHANISMS OF DEVELOPMENT | 2000年 / 90卷 / 01期

基金：

日本学术振兴会;

关键词：

chick embryo; TGF beta; lefty1; antivin; left-right asymmetry; notochord; prospective floorplate; lateral plate mesoderm;

D O I：

10.1016/S0925-4773(99)00232-4

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/leftyl cDNA and studied its expression pattern during early chick development. We found that antivin/leftyl is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：115 / 118

页数：4

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