Yersinia type III secretion:: send in the effectors

被引：305

作者：

Cornelis, GR

机构：

[1] Univ Basel, Bioctr, CH-4056 Basel, Switzerland

[2] Catholic Univ Louvain, Christian de Duve Inst Cellular Pathol, B-1200 Brussels, Belgium

来源：

JOURNAL OF CELL BIOLOGY | 2002年 / 158卷 / 03期

关键词：

bacterial pathogenesis; Yersinia; Yops; translocation; type III secretion;

D O I：

10.1083/jcb.200205077

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors into cells of the host immune system where they inhibit signaling cascades and block the cells' response to infection. Understanding the molecular mechanisms of this system has provided insight into the processes of phagocytosis and inflammation.

引用

页码：401 / 408

页数：8

共 73 条

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