Antioxidant and cytotoxic activities of Retama raetam subsp Gussonei

被引：25

作者：

Conforti, F ^{[1
]}

Statti, G

Tundis, R

Loizzo, MR

Bonesi, M

Menichini, F

Houghton, PJ

机构：

[1] Univ Calabria, Dept Pharmaceut Sci, I-87036 Arcavacata Di Rende, CS, Italy

[2] Kings Coll London, Dept Pharm, London, England

来源：

PHYTOTHERAPY RESEARCH | 2004年 / 18卷 / 07期

关键词：

Retama raetam subsp gussonei; antioxidant; cytotoxicity; liposomes;

D O I：

10.1002/ptr.1496

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The aim of this study was to evaluate the in vitro antioxidant and cytotoxic activities of the methanol extracts of Retama raetam subsp. gussonei leaves and seeds. The antioxidant activity of the extracts was assessed by means of two different tests: (1) bleaching of the stable 2,2-diphenyl-1-pierylhydrazil (DPPH) radical; and (2) lipid peroxidation of liposomes which were prepared from bovine brain extract. In both tests used leaves extract showed a significant antioxidant effect. The extract of leaves also demonstrated a good cytotoxic activity against COR-L23 (large cell carcinoma) tell line. Copyright (C) 2004 John Wiley Sons, Ltd.

引用

页码：585 / 587

页数：3

共 16 条

[1]

Abdel Halim O B, 1997, Acta Pharm Hung, V67, P241

[2] NATURAL-PRODUCTS AS A SOURCE OF POTENTIAL CANCER CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS [J].