Anxiety sensitivity and depression in multiple chemical sensitivities and asthma

被引:37
作者
Caccappolo-van Vliet, E
Kelly-McNeil, K
Natelson, B
Kipen, H
Fiedler, N
机构
[1] UMDNJ, Robert Wood Johnson Med Sch, Dept Environm & Community Med, Piscataway, NJ 08854 USA
[2] DVAMC, Ctr Environm Hazards Res, E Orange, NJ USA
[3] Columbia Presbyterian Med Ctr, Sergievsky Ctr, New York, NY 10032 USA
[4] UMDNJ, New Jersey Med Sch, Dept Neurosci, Piscataway, NJ USA
关键词
D O I
10.1097/01.jom.0000026646.83602.bb
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Patients with sensitivities to multiple chemicals report symptoms of cognitive dysfunction, respiratory distress, and mood disturbance. Lifetime and current psychiatric disorders, personality traits associated with symptom reporting, and tests of cognitive function were compared between 30 subjects with Multiple Chemical Sensitivities (MCS), 19 asthmatics, and 31 healthy controls. Relative to asthmatics and controls, more MCS subjects met criteria for current depression and somatization disorder. MCS subjects and asthmatics scored significantly higher than controls on scales of chemical odor intolerance and anxiety sensitivity, both of which were significant predictors of physical symptoms. Few differences on objective neuropsychological tests were noted. However, MCS subjects with comorbid depression performed significantly worse on a verbal memory test relative to asthmatics but not to controls. Anxiety and depression are significant contributors to the physical and cognitive symptoms of MCS subjects.
引用
收藏
页码:890 / 901
页数:12
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