Synthesis and properties of 10,11-dibenzimidazolyl-10,11-didesmethyl-hypericin - The first heterocyclically substituted hypericin derivative

被引：10

作者：

Lackner, B ^{[1
]}

Etzlstorfer, C ^{[1
]}

Falk, H ^{[1
]}

机构：

[1] Johannes Kepler Univ, Inst Organ Chem, A-4040 Linz, Austria

来源：

MONATSHEFTE FUR CHEMIE | 2004年 / 135卷 / 09期

关键词：

heterocycles; phenanthroperylenequinone; photodynamic therapy; semiempirical calculations; tautomerism;

D O I：

10.1007/s00706-004-0186-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of the first heterocyclically substituted title hypericin derivative was achieved starting from 6-benzimidazolyi-tri-O-methyl-6-desmethylemodin. The chemical as well as photochemical properties of this unique hypericin derivative, which might constitute a new photodynamic therapy agent, are reported.

引用

页码：1157 / 1166

页数：10

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