Effect of supplementation with folic acid throughout pregnancy on plasma homocysteine concentration

被引：10

作者：

Ellison, J

Clark, P ^{[1
]}

Walker, ID

Greer, IA

机构：

[1] Univ Dundee, Ninewells Hosp & Med Sch, Dept Transfus Med, Dundee DD1 9SY, Scotland

[2] Univ Glasgow, Royal Infirm, Dept Obstet & Gynaecol, Glasgow G31 2ER, Lanark, Scotland

[3] Univ Glasgow, Royal Infirm, Dept Haematol, Glasgow G31 2ER, Lanark, Scotland

来源：

THROMBOSIS RESEARCH | 2004年 / 114卷 / 01期

关键词：

pregnancy; plasma homocysteine; homocysteine; folic acid;

D O I：

10.1016/j.thromres.2004.04.006

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

High circulating homocysteine concentrations in pregnancy are associated with adverse pregnancy outcomes. We have demonstrated that folic acid supplementation throughout pregnancy suppresses the change in plasma homocysteine concentration which occurred in our study group. This simple, safe and inexpensive intervention may therefore play a preventative role. Further large-scale studies are required to determine the effectiveness of folic acid supplementation in the prevention of poor obstetric outcomes.

引用

页码：25 / 27

页数：3

共 10 条

[1]

CIKOT R, 2001, BR J NUTR, V85, P48

[2]

Thrombosis in pregnancy: maternal and fetal issues [J].